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Can a daily supplement ease knee arthritis pain?

NCT ID NCT07643662

Symptom relief Sponsor: University of Malaya Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study will test Mobithron Xtra, an oral supplement containing hyaluronic acid, collagen, and Boswellia extract, in 100 adults with knee osteoarthritis. Participants will take it once daily for 3 months while researchers track changes in pain, stiffness, and daily function using standard questionnaires. The goal is to see if this supplement can help manage symptoms without surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Mobithron Xtra (hyaluronic acid, undenatured type II collagen, Boswellia serrata extract)
What this could lead to
If it works, this could provide a non-surgical option to ease knee pain and stiffness in osteoarthritis.
What could go wrong
This is a small, early observational study with no control group, so results may not prove effectiveness. Participants cannot take common painkillers, which may limit real-world use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 100 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jul 2026

An estimate. Start dates often move.

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Prospective, multi-centred, observational cohort study, whereby patients fulfilling inclusion and exclusion criteria will be recruited prospectively at general practitioner clinics located throughout Malaysia.

Ages

40 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults ≥40 years with primary knee osteoarthritis (OA) * Radiographic diagnosis of primary knee OA (Grade 2 or 3 on Kellgren-Lawrence scale) * Stable physiotherapy regimen for ≥3 months (if applicable). * Baseline VAS score ≥ 5 * No prior surgical intervention for the affected knee Exclusion Criteria: * Secondary OA (such as post-traumatic and inflammatory arthritis) * Grade IV Primary OA * Patients on analgesia (e.g., paracetamol, NSAIDs) * Patients on Mobithron (P/Advance/Xtra) or glucosamine products * Recent intra-articular injections within 6 months * Recent/planned knee surgery within 3 months * Severe comorbidities or cognitive impairment

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Conditions

The condition(s) this trial relates to.

osteoarthritis osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Osteoarthritis (OA) of the knee

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Faculty of Medicine

    Kuala Lumpur, Kuala Lumpur, 50603, Malaysia

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