Tiny power plants in cells may hold key to bone health
NCT ID NCT05483738
First seen Oct 31, 2025 · Last updated Jun 19, 2026 · Updated 28 times
Summary
This study looks at how problems with mitochondria—the tiny power plants inside our cells—might affect bone health. Researchers will compare 30 people with certain genetic mitochondrial variants to healthy volunteers. They will take blood samples, bone marrow, and small bone biopsies to measure how bone cells use energy and grow. The goal is to understand if mitochondrial dysfunction leads to weaker bones.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Dept. of Clinical Genetics
Aalborg, Denmark
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this study could reveal why people with mitochondrial diseases often have bone problems, pointing toward future treatments to protect bone health.
What could go wrong
This is an early observational study with only 30 participants, so results may not apply to everyone. It aims to understand the disease, not test a treatment.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.