Could a common antidepressant ease two side effects of brain cancer treatment?
NCT ID NCT03935685
First seen Nov 01, 2025 · Last updated May 22, 2026 · Updated 34 times
Summary
This study looks at whether mirtazapine, an antidepressant, can help reduce depression, nausea, and vomiting in people with a type of brain cancer (glioma) who are taking the chemotherapy drug temozolomide. About 120 adults with newly diagnosed glioma and depression will take mirtazapine for 8 weeks. Researchers will track changes in mood, nausea, weight, and any side effects.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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UC Irvine Health/Chao Family Comprehensive Cancer Center
Orange, California, 92868, United States
Conditions
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