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Mindfulness meets nerve zapping: a new way to curb heavy drinking?

NCT ID NCT07516873

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study explores whether combining a week of mindfulness training with a gentle nerve stimulation device (RAVANS) can help young heavy drinkers reduce their alcohol intake. Fifty participants aged 21-29 will practice mindfulness and receive either active or inactive stimulation during lab visits. Researchers will measure heart rate variability and self-reported drinking to see if the combo is acceptable and shows promise.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Respiratory-gated Auricular Vagal Afferent Nerve Stimulation (RAVANS) device
What this could lead to
If it works, this could point toward a non-drug, mind-body approach to help young adults cut back on heavy drinking.
What could go wrong
This is a very early, small feasibility study with only 50 participants. It is not designed to prove effectiveness, and the results may not apply to broader populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 50 people

The number the study aims to enrol. It can still change while the study runs.

Started

Mar 2026

Expected to finish

Aug 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

21 to 29 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Currently living in Massachusetts. * Aged 21-29 years old. * Consume either more than 14 standard drinks of alcohol per week OR at least 5 standard drinks in one day per week (in past 30 days). * Have sufficient English fluency to understand procedures and questionnaires. * Have the capacity and ability to provide informed consent. * Scores at least 15 points on the PACS at screening. Participants who score between 10 and 14 pts will undergo additional doctoral-level review to assess eligibility. Exclusion Criteria: * Current or past diagnosis of a substance use disorder based on the Quick Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-5) Module C (Substance Use Disorders). * Active prescription for sedative/hypnotics, opioids, or anesthetic medications. * Active prescription for medications used to treat alcohol use disorder (AUD), e.g., naltrexone, disulfiram, acamprosate, etc. * Active psychosis or schizophrenia-spectrum disorder diagnosis. * Bipolar I disorder history or severe level of mania. * Severe symptoms of PTSD. * Acute suicidality or self-injurious behavior. * Cognitive inability as demonstrated by the inability to complete an informed consent assessment with \>90% accuracy after 2 attempts. * Current participation in another experimental intervention research study. * Current daily mindfulness practice \>10 minutes per day. * Participation in an 8-week intensive Mindfulness-Based Intervention or residential meditation retreat in past 3 years. * Expected medical hospitalization in the next 2 months; or are currently pregnant. * Expected incarceration in the next 2 months. * Presence of electronic implants, such as heart pacemakers, defibrillators, or pumps. * Presence of a cardiac rhythm disorder. * History of seizures. * Presence of skin disorders or malignant diseases in the area in or around the left ear. * Lack of alcohol craving as assessed by the PACS during screening (score of \< 10 points).

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As listed by the trial registrant

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How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

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Contacts and locations

Locations

  • Center for Mindfulness and Compassion

    RECRUITING

    Malden, Massachusetts, 02148, United States

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