Mindfulness meets nerve zapping: a new way to curb heavy drinking?
NCT ID NCT07516873
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study explores whether combining a week of mindfulness training with a gentle nerve stimulation device (RAVANS) can help young heavy drinkers reduce their alcohol intake. Fifty participants aged 21-29 will practice mindfulness and receive either active or inactive stimulation during lab visits. Researchers will measure heart rate variability and self-reported drinking to see if the combo is acceptable and shows promise.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Respiratory-gated Auricular Vagal Afferent Nerve Stimulation (RAVANS) device
- What this could lead to
- If it works, this could point toward a non-drug, mind-body approach to help young adults cut back on heavy drinking.
- What could go wrong
- This is a very early, small feasibility study with only 50 participants. It is not designed to prove effectiveness, and the results may not apply to broader populations.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 50 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Mar 2026
- Expected to finish
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Aug 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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21 to 29 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Currently living in Massachusetts. * Aged 21-29 years old. * Consume either more than 14 standard drinks of alcohol per week OR at least 5 standard drinks in one day per week (in past 30 days). * Have sufficient English fluency to understand procedures and questionnaires. * Have the capacity and ability to provide informed consent. * Scores at least 15 points on the PACS at screening. Participants who score between 10 and 14 pts will undergo additional doctoral-level review to assess eligibility. Exclusion Criteria: * Current or past diagnosis of a substance use disorder based on the Quick Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-5) Module C (Substance Use Disorders). * Active prescription for sedative/hypnotics, opioids, or anesthetic medications. * Active prescription for medications used to treat alcohol use disorder (AUD), e.g., naltrexone, disulfiram, acamprosate, etc. * Active psychosis or schizophrenia-spectrum disorder diagnosis. * Bipolar I disorder history or severe level of mania. * Severe symptoms of PTSD. * Acute suicidality or self-injurious behavior. * Cognitive inability as demonstrated by the inability to complete an informed consent assessment with \>90% accuracy after 2 attempts. * Current participation in another experimental intervention research study. * Current daily mindfulness practice \>10 minutes per day. * Participation in an 8-week intensive Mindfulness-Based Intervention or residential meditation retreat in past 3 years. * Expected medical hospitalization in the next 2 months; or are currently pregnant. * Expected incarceration in the next 2 months. * Presence of electronic implants, such as heart pacemakers, defibrillators, or pumps. * Presence of a cardiac rhythm disorder. * History of seizures. * Presence of skin disorders or malignant diseases in the area in or around the left ear. * Lack of alcohol craving as assessed by the PACS during screening (score of \< 10 points).
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Center for Mindfulness and Compassion
RECRUITINGMalden, Massachusetts, 02148, United States
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