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Mindfulness may ease Parkinson's symptoms without drugs

NCT ID NCT03998462

Symptom relief Sponsor: VA Office of Research and Development Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether an 8-week mindfulness program (MBSR) could improve quality of life, thinking, and mood in 107 people with Parkinson's disease. Participants were randomly assigned to MBSR or a supportive education group, with sessions held online due to COVID-19. The goal was to see if mindfulness training provides lasting benefits beyond standard care.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Mindfulness Based Stress Reduction (MBSR) - a structured program of weekly group sessions and a retreat, delivered online
What this could lead to
If it works, this could offer a drug-free way to help people with Parkinson's feel better day-to-day and manage stress.
What could go wrong
This is a completed study with 107 participants, but results may not apply to everyone with Parkinson's. The online format during COVID may have affected outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

107 people

The number who actually took part.

Started

Jan 2020

Finished

Nov 2024

Lead sponsor

A government agency

The lead sponsor is a US federal agency other than the NIH.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Clinical diagnosis of PD based on UK Brain Bank Criteria 2. 40 years of age or older Exclusion Criteria: 1. Secondary causes of Parkinsonism (e.g. corticobasal degeneration, progressive supranuclear palsy, drug-induced parkinsonism) 2. Other neurological conditions (e.g. stroke) 3. Clinical diagnosis of dementia based on any previous neuropsychological testing 4. Psychosis, antipsychotic treatment or treatment for substance abuse 5. Uncorrected vision or hearing to adequately participate in the intervention 6. Prior formal training in MBSR or regular current MBSR practice 7. Inability to use a computer or technology for participation 8. Active/current suicidal ideation

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Conditions

The condition(s) this trial relates to.

Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Parkinson's disease

Contacts and locations

Locations

  • VA San Diego Healthcare System

    San Diego, California, 92161-0002, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.