Mindfulness meets exposure: a gentler path to treating OCD?
NCT ID NCT07484750
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a new 10-week group therapy called Mindfulness-Based Exposure Therapy (MBET) for people with obsessive-compulsive disorder (OCD). The therapy combines mindfulness training with exposure exercises to help patients better manage distress and complete treatment. Researchers aim to see if this approach is more tolerable and effective than standard exposure therapy. The trial is recruiting 64 participants aged 16 to 55 with moderate to severe OCD.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- mindfulness-based exposure therapy (group behavioral intervention)
- What this could lead to
- If it works, this could offer a more tolerable treatment option for people with OCD who find standard exposure therapy too distressing.
- What could go wrong
- This is a small, early-stage trial with only 64 participants. The therapy may not prove more effective than existing treatments, and results may not apply to all OCD patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 64 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Feb 2026
- Expected to finish
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Jun 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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16 to 55 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Have a primary diagnosis of Obsessive-Compulsive Disorder (OCD) according to DSM-5 criteria * Are between 16 and 55 years of age (inclusive) * Have a Yale-Brown Obsessive Compulsive Scale (Y-BOCS) total score ≥ 16 * Have an education level of junior high school or above * Are medication-free or have been stabilized on psychotropic medication for at least 8 weeks * Have sufficient visual and auditory capabilities to complete study assessments * Are willing to participate and provide written informed consent Exclusion Criteria: * Meet DSM-5 criteria for any other psychiatric disorder besides OCD * Have severe OCD symptoms that prevent completion of assessments * Exhibit active suicidal ideation or high suicide risk * Have a serious somatic disease, central nervous system disease, or substance abuse history * Are pregnant, breastfeeding, or planning pregnancy * Have metal implants contraindicated for MRI (e.g., pacemakers, intracranial clips, metal dentures, arterial stents, joint fixations)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Shanghai mental health center
RECRUITINGShanghai, Shanghai Municipality, 200030, China