Lupus blood test clues: tiny molecules under the microscope
NCT ID NCT07252141
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at two substances in the blood—microRNA-101-3p and autotaxin—in 40 adults with lupus and 40 healthy volunteers. Researchers want to see if these markers are different in people with lupus and if they are linked to how active the disease is. No treatments or drugs are given; this is purely an observation study to gather knowledge.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 40 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Dec 2025
An estimate. Start dates often move.
- Expected to finish
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Jul 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study will include 40 patients diagnosed with systemic lupus erythematosus (SLE) according to the 2012 Systemic Lupus International Collaborating Clinics (SLICC) classification criteria and 40 age- and sex-matched healthy controls. Patients will be recruited from the Rheumatology and Rehabilitation Department and Internal Medicine Department (Rheumatology Unit) at Assiut University Hospitals, Egypt.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Study Population: Adult patients diagnosed with systemic lupus erythematosus and healthy matched controls. Inclusion Criteria: * \- Age ≥ 18 years * Diagnosis of SLE according to 2012 SLICC criteria * Willingness to participate and provide informed consent Exclusion Criteria: Age \< 18 years * Pregnancy or lactation * Active infections or malignancy * Co-existing autoimmune diseases * Refusal to participate
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a Three-Drug combo quiet lupus kidney flares?
- Can a new antibody tame lupus flares?
- Can a single infusion of reprogrammed immune cells quiet lupus kidney disease?
- Eye tests could spot silent vision damage in lupus patients