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A skin needling trick may erase red stretch marks
NCT ID NCT07795515
First seen Aug 31, 2026 · Last updated Sep 11, 2026 · Updated 3 times
Summary
This trial tests whether adding tranexamic acid to microneedling improves early stretch marks, called striae rubra, better than microneedling alone. Adults with matching stretch marks on both sides of the body receive the acid on one side and a placebo on the other, with sessions every three weeks for up to five visits. Researchers compare the two sides to see which fades more.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Topical tranexamic acid solution (100 mg/mL) applied before microneedling
- What this could lead to
- If it works, this could offer a more effective way to fade early stretch marks, improving skin appearance without surgery.
- What could go wrong
- The trial is small and early, and the improvement may be modest or no better than microneedling alone. Side effects like redness or irritation are possible.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 50 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Oct 2026
An estimate. Start dates often move.
- Expected to finish
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Jun 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients of both gender aged ≥18 years, clinically and dermoscopically diagnosed with bilateral symmetrical striae rubra (present on corresponding anatomical sites on both sides of the body with approximately symmetrical distribution and similar clinical appearance (color, width, and stage of evolution)). and willing to participate and sign informed consent Exclusion Criteria: * • Striae alba. * Pregnancy or lactation. * History of keloids or hypertrophic scars. * Active skin infection in treatment area. * Patients using other modalities of treatment for over the last 3 months. * Patients with bleeding disorders or on anticoagulant therapy. * Patients using drugs that exacerbate the striae as systemic corticosteroids in the preceding 3 months or topical corticosteroid in the preceding one month.
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Get notified about this study
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Faculity of Medicine ,Sohag University
Sohag, Egypt