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Dentists study which cavity removal method keeps mouth bacteria healthiest

NCT ID NCT07538089

Knowledge-focused Sponsor: Nuh Naci Yazgan University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how two ways of cleaning cavities—removing all decayed tissue versus leaving some softer tissue near the nerve—change the types of bacteria left in the tooth. Researchers will take samples from 48 adults with cavities and analyze the DNA of the bacteria. The goal is to find which method better reduces harmful germs while keeping helpful ones, helping dentists choose the best approach for long-term oral health.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help dentists choose cavity removal methods that better reduce harmful bacteria and preserve healthy ones.
What could go wrong
This is a small, early-stage observational study with only 48 participants. It does not test a treatment, so results may not lead to immediate changes in dental care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

48 people

The number who actually took part.

Started

Feb 2026

Expected to finish

Aug 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 40 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Permanent molar or premolar teeth with carious lesions located on the occlusal surface and extending no deeper than the middle third of dentin * Individuals with good oral hygiene * Absence of clinical signs or symptoms of periapical pathology * Teeth in occlusion with the opposing dentition * Individuals aged between18-40 years * Individuals who provide written informed consent Exclusion Criteria: * Teeth with pulpal exposure or irreversible pulpitis * Presence of periapical pathology * Poor oral hygiene * Patients with systemic conditions affecting oral health or healing * Use of antibiotics within the last 3 months * Pregnant or lactating individuals

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Conditions

The condition(s) this trial relates to.

dental caries

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Caries,dental

Contacts and locations

Locations

  • Nuh Naci Yazgan University Faculty of Dentistry

    Kayseri, Kocasinan, 38170, Turkey (Türkiye)

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