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Simple test could catch silent brain fog in liver disease

NCT ID NCT07272707

Knowledge-focused Sponsor: Sohag University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at a thinking and coordination test called PHES to find early, hidden brain problems in people with stable liver cirrhosis. About 150 patients and some healthy volunteers will take the test. The goal is to see how well the test catches these issues before they get worse.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 150 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Dec 2025

An estimate. Start dates often move.

Expected to finish

Sep 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Group 1: Cirrhotic Patients (Cases) Compensated cirrhotic patients aged 18-70 years undergoing PHES testing. Group 2: Healthy Volunteers (Controls) Healthy adults aged 18-70 years with no chronic disease and normal cognitive function.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Inclusion Criteria (Cirrhotic Patients): 1. Age 18-70 years. 2. Diagnosed compensated liver cirrhosis, regardless of etiology. 3. Able to read and write. 4. Adequate vision, hearing, and physical ability to perform the PHES tests. Inclusion Criteria (Healthy Controls): <!-- --> 1. Age 18-70 years. 2. No chronic medical, neurological, psychiatric, renal, or cardiac disease. 3. Able to read and write. 4. Adequate cognition, hearing, vision, and physical ability. Exclusion Criteria: <!-- --> 1. Chronic liver disease. 2. Neuropsychiatric illness. 3. Use of psychoactive medications. 4. Illiteracy.

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Conditions

The condition(s) this trial relates to.

cirrhosis of liver hepatic encephalopathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Minimal hepatic encephalopathy

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  2. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

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Other studies related to the condition(s) this trial covers.