Protein clue could predict endometrial cancer outcomes
NCT ID NCT06861855
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study will examine tissue samples from 50 people with type 1 endometrial cancer to measure levels of a protein called METTL-14. Researchers want to see if higher or lower amounts of this protein are linked to how aggressive the cancer is and how long patients live without the disease coming back. The goal is to better understand which patients might need more or less treatment, but this study does not test any new drug or therapy.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 50 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2025
An estimate. Start dates often move.
- Expected to finish
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Oct 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
endometrial carcinoma
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Female participants only
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Cases of type1endometrial carcinoma with: 1. Hystrectomy operation 2. Available full clinical data about patient (age, complaint, findings in clinical examination). 3. Full data about previous biopsy and radiology. 4. Full data about patient survival, disease progression and history of chemotherapy for three years. Exclusion Criteria: * 1\. Any case of type 1 endometrial carcinoma with missing clinical, radiologic or follow up data. 2\. Cases with no available H\&E stained slides or formalin fixed paraffin embedded block. 3.D\&C.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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AssuitU
Asyut, Egypt
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Other studies related to the condition(s) this trial covers.
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