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Hope for leprosy patients: common arthritis drug may replace risky steroids

NCT ID NCT03775460

First seen Nov 01, 2025 · Last updated May 22, 2026 · Updated 33 times

Summary

This study tests if methotrexate, a cheap and widely available drug, can help control Erythema Nodosum Leprosum (ENL), a painful complication of leprosy. ENL often requires long-term steroids, which have serious side effects. The trial involves 550 adults and aims to see if methotrexate reduces the need for steroids over 48 weeks.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • ALERT

    Addis Ababa, Ethiopia

  • Anandaban Hospital

    Kathmandu, Nepal

  • Bombay Leprosy Project

    Mumbai, India

  • FIOCRUZ

    Rio de Janeiro, Brazil

  • Soetomo Hospital

    Surabaya, Indonesia

  • TMLI Bangladesh/ DBLM hospital

    Dhaka, Bangladesh

  • The Leprosy Mission Trust

    Delhi, India

Conditions

Explore the condition pages connected to this study.