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Diabetes drug shows promise against deadly brain tumor

NCT ID NCT04945148

First seen Nov 21, 2025 · Last updated May 22, 2026 · Updated 20 times

Summary

This study tests whether adding metformin, a common diabetes drug, to standard radiation and chemotherapy can help people with a specific type of glioblastoma (a fast-growing brain cancer). The trial includes about 64 adults whose tumors have a unique energy profile. The goal is to see if this combination can slow tumor growth and improve survival.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Foch Hospital

    RECRUITING

    Suresnes, Hauts de Seine, 92150, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hôpital Neurologique Pierre Wertheimer

    RECRUITING

    Bron, Lyon, 69500, France

    Contact Email: •••••@•••••

  • Istituto Nazionale Carlo Besta

    NOT_YET_RECRUITING

    Milan, Milano, 20131, Italy

    Contact Email: •••••@•••••

  • Pitié Salpêtrière Hospital

    RECRUITING

    Paris, PARIS, 75013, France

    Contact Email: •••••@•••••

  • Saint Louis Hospital

    RECRUITING

    Paris, Paris, 75010, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Spidali Riuniti Di Livorno

    NOT_YET_RECRUITING

    Livorno, Toscana Nord Ouest, 57100, Italy

    Contact Email: •••••@•••••

  • Timone Hospital

    RECRUITING

    Marseille, Marseille, 13354, France

    Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.