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Could a diabetes drug help children's jaw bones heal stronger?

NCT ID NCT07536620

First seen Apr 30, 2026 · Last updated May 23, 2026 · Updated 5 times

Summary

This study tests whether adding metformin gel to a standard bone graft improves bone quality in children born with a gap in the upper jaw (alveolar cleft). 36 children aged 8-12 will receive either a bone graft mixed with metformin or a placebo. The goal is to see if metformin helps the bone become denser and stronger.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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