New DNA test could uncover hidden eye infections
NCT ID NCT06974162
First seen Nov 20, 2025 · Last updated Jun 23, 2026 · Updated 26 times
Summary
This study tests a new diagnostic test called metagenomic sequencing on eye fluid from 36 adults with unexplained eye inflammation. The test looks for DNA from almost any infection (bacteria, virus, fungus, parasite) that standard tests miss. If it works, it could help doctors find the cause and choose the right treatment.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Moorfields Eye Hospital NHS Foundation Trust
RECRUITINGLondon, United Kingdom
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
metagenomic sequencing of aqueous humor
What this could lead to
If successful, this could help doctors identify hidden infections causing eye inflammation, leading to more targeted treatments.
What could go wrong
This is a small, early-stage diagnostic study with only 36 participants. The technique may not find infections in all cases, and results may not change treatment outcomes.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.