Fasting for 24 hours: scientists peer inside your immune system
NCT ID NCT07527208
First seen Jun 27, 2026 · Last updated Sep 11, 2026 · Updated 2 times
Summary
This study looks at what happens to your immune cells when you fast for 24 hours. Researchers want to understand how the body's switch from using sugar to burning fat for energy changes the way immune cells work. The study involves 28 healthy adults aged 18-40. No treatment or drug is being tested—only the effects of fasting are measured.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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28 people
The number who actually took part.
- Started
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Jun 2026
- Finished
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Sep 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 40 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Apparently healthy * Age 18-40y at the time of recruitment * BMI ≥ 18.5 and ≤ 24.9 kg/m2 * Willing to participate in all study activities during the 3-day intervention * Signed informed consent Exclusion Criteria: * Diagnosed with any chronic medical condition that can interfere with the study outcome (e.g., cardiovascular disease, cancer, diabetes mellitus type 1 or 2, liver disease, pulmonary disease, renal disease, inflammatory bowel disease, thyroid disease, long COVID, PASC) * Bleeding disorder (e.g., Hemophilia A/B, Von Willebrand Disease, or low platelets), current anemia or current use of blood thinners or anticoagulants (e.g. warfarin, heparin) * Any acute or chronic infection disease or fever in the past month * Antibiotic use in the past 2 months * Use of any prescribed medications (incl. GLP-1 agonists), except for contraceptives * Usage of recreational drugs in the last three months * Unstable body weight (weight gain or loss \>5% of total BW in the past three months) * Following any restrictive diet within one month of starting the study (for example a ketogenic diet or weight loss diet) * Fasted for 16 hours or longer in the past week * History of an eating disorder (e.g., anorexia nervosa, bulimia nervosa, or binge eating disorder) * Allergic to one or more components of the standardized meal and/or shake (i.e., milk, wheat, and soy) * Average alcohol intake that exceeds 1 consumption/day or 7 consumptions/week over the past month * Tobacco smoker or regular use of nicotine products * Donated or intend to donate blood from 2 months before the study until the end of the study * Being pregnant or lactating * Participation in another biomedical study during this study
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Human Metabolic Research Unit, Division of Nutritional Sciences. Cornell University
Ithaca, New York, 14853, United States
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Other studies related to the condition(s) this trial covers.
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