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New dressing combo aims to ease anal pain during rectal cancer radiation

NCT ID NCT06837831

First seen Apr 22, 2026 · Last updated Jun 18, 2026 · Updated 10 times

Summary

This study tests whether a special dressing (Mepilex Lite) placed inside the anal canal, combined with a pain-relief suppository (indomethacin), can better treat painful skin damage caused by radiation therapy for rectal cancer. About 274 adults who develop moderate to severe anal skin irritation during their first round of radiation will be randomly assigned to get either standard care plus the suppository, or the same plus the dressing. The main goal is to see if the dressing improves skin healing and reduces pain after two weeks of treatment.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The First Affiliated Hospital of Shandong First Medical University

    RECRUITING

    Jinan, Shandong, 250000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

anal canal cancer radiodermatitis rectal cancer rectal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.