Could your period predict Post-Surgery sickness?
NCT ID NCT07242209
First seen Jun 25, 2026 · Last updated Jul 08, 2026 · Updated 3 times
Summary
This study watches 60 women aged 18-40 having nose surgery to see if their menstrual cycle phase affects nausea and vomiting afterward. Researchers also check if a drug called sugammadex, used during anesthesia, changes the risk. No new treatments are tested—just observation of routine care.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could help doctors predict and manage nausea after surgery based on menstrual cycle phase.
- What could go wrong
- This is a small observational study, so it can't prove cause and effect. Results may not apply to all women or surgeries.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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60 people
The number who actually took part.
- Started
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Dec 2025
- Finished
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May 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study population consists of women of reproductive age (18-40 years) who are scheduled to undergo septorhinoplasty surgery under general anesthesia. Eligible participants have a regular menstrual cycle and are classified as ASA physical status I or II. Participants with irregular menstrual cycles, unknown last menstrual period, pre-menopausal or menopausal status, or those receiving hormonal supplementation are excluded. Other exclusion criteria include pregnancy, breastfeeding, ASA III-IV status, high risk for postoperative nausea and vomiting (Apfel score ≥3), history of drug allergy, and surgery duration exceeding 3 hours. Data will be collected prospectively from anesthesia records, postoperative assessments, and standardized questionnaires evaluating postoperative nausea and vomiting (PONV).
- Ages
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18 to 40 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Female sex * Age between 18 and 40 years * Regular menstrual cycle * Scheduled for ENT (ear, nose, and throat) surgery * Classified as ASA physical status I or II Exclusion Criteria: * Irregular menstrual cycle * Unknown date of last menstrual period * Receiving estrogen and/or progesterone supplementation * Pre-menopausal or menopausal status * Pregnant * Breastfeeding * Classified as ASA physical status III or IV * Apfel score ≥ 3 * History of drug allergy * Surgery duration exceeding 3 hours * Age \<18 or \>40 years
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Sakarya University-Anesthesiology and Reanimation Department
Sakarya, Serdivan, 54050, Turkey (Türkiye)
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