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Membrane sweeping may boost vaginal birth after C-Section

NCT ID NCT06103071

Disease control Sponsor: HITEC-Institute of Medical Sciences Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether membrane sweeping—a procedure where a doctor gently separates the amniotic sac from the cervix—can help start labor and lead to a vaginal birth in women who have had one previous C-section. 384 women were enrolled. The goal was to see if this simple technique could reduce the need for repeat C-sections.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
membrane sweeping (a procedure where a doctor gently separates the amniotic sac from the cervix to encourage labor)
What this could lead to
If effective, membrane sweeping could offer a simple, low-cost way to help women with a prior C-section achieve a vaginal birth, reducing the need for repeat C-sections.
What could go wrong
This is a single, completed study in Pakistan with 384 participants. Results may not apply to other populations, and the procedure may not work for everyone. Risks include discomfort, bleeding, or infection.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

384 people

The number who actually took part.

Started

Jan 2023

Finished

Jul 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 45 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 1\. Women willing for vaginal birth after lower segment cesarean section from 37 weeks of gestation to 40 weeks. 2\. Previous one caesarean section for non-recurrent cause 3. Singleton pregnancy 4. Cephalic presentation Exclusion Criteria: 1. Previous uterine rupture 2. Major degree placenta previa 3. Any medical disorder like PIH, diabetes 4. Bad obstetrics history

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Vaginal birth after cesarean section

Contacts and locations

Locations

  • HIT hospital

    Rawalpindi, Punjab Province, 47080, Pakistan