Melanoma mystery solved? 232 patient records reveal clues to better treatment
NCT ID NCT07256184
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked back at the medical records of 232 adults with advanced melanoma to find out which factors—like patient traits, tumor features, and treatments—are linked to better outcomes. Researchers reviewed data from people treated between 2022 and 2024 at hospitals in Türkiye. The goal is to use this real-world information to help doctors choose the best treatment for each patient.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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232 people
The number who actually took part.
- Started
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Nov 2022
- Finished
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Dec 2024
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Adult patients with metastatic malignant melanoma treated with standard systemic therapy, including immune checkpoint inhibitors, BRAF/MEK inhibitors, or chemotherapy. Data were extracted retrospectively from electronic medical records across multiple oncology centers in Türkiye.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥18 years * Histologically or cytologically confirmed metastatic malignant melanoma * Received ≥1 line of systemic therapy * Complete baseline and follow-up data * At least one measurable lesion or clinical response assessment * Managed between November 2022 - December 2024 at participating centers Exclusion Criteria: * Incomplete clinical or pathological data * Uncertain or revised diagnosis * Metastasis developing outside the inclusion window * Another primary malignancy (except allowed types) * Lost to follow-up before first response assessment
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Ankara Etlik City Hospital
Ankara, Yenimahalle, 06210, Turkey (Türkiye)
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Gazi University, Medical Oncology Department
Ankara, Çankaya, Turkey (Türkiye)
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