Blood test could reveal how melanoma changes during treatment
NCT ID NCT02133222
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at 22 people with advanced (Stage IV) melanoma to see if DNA floating in their blood could show genetic changes in their cancer before and after chemotherapy. Researchers compared the DNA found in blood samples with the original tumor's genetics. The goal was to learn how tumors evolve during treatment, not to test a new therapy.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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22 people
The number who actually took part.
- Start date
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May 2014
- Finished
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Aug 2016
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age\>18 years * Surgical biopsy for histologic diagnostic * All melanoma subtypes * Known genotype BRAF V600 * Affiliation social security * Consent form signed Exclusion Criteria: * Patient with histories of cancer or the other synchronous cancer * Pregnant women * Breast-feeding women * Vulnerable patients: major under guardianship; patient deprived of its rights
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CHU de Nice
Nice, 06000, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.