Blood test showdown: which method spots melanoma cells better?
NCT ID NCT01558349
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compared two blood test methods, EPISPOT and CellSearch, to see how well they detect circulating melanoma cells in people with advanced melanoma. Researchers took blood samples from 73 participants, including patients with stage 4 melanoma and hospitalized controls without cancer. The goal was to find out which technique is more accurate at spotting these cells, which could help improve monitoring of the disease.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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73 people
The number who actually took part.
- Started
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Jun 2013
- Finished
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Jun 2017
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The two cohorts in this study are composed of (1) patients suffering from metastatic melanome and (2) hospitalized patients with no history of cancer.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * The patient must have given his/her informed and signed consent * The patient must be insured or beneficiary of a health insurance plan * The patient is available, within the hours of his/her normally scheduled medical care, for blood sampling at 8 am and 4 pm on the same day. Inclusion Criteria for patients: * Stage 4 melanoma, without other associated neoplasms Inclusion Criteria for controls: * Patient without cancer, nor history of cancer Exclusion Criteria: * The patient is participating in another study * The patient is in an exclusion period determined by a previous study * The patient is under judicial protection, under tutorship or curatorship * The patient refuses to sign the consent * It is impossible to correctly inform the patient * The patient is pregnant, parturient, or breastfeeding * The patient has a contra-indication for a treatment used in this study Exclusion criteria for patients: * Stage 1 to 3 melanoma, or other types of cancer Exclusion criteria for controls: * History of cancer
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CHU de Montpellier - Hôpital Saint-Eloi
Montpellier, 34295, France
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CHU de Nîmes - Hôpital Universitaire Carémeau
Nîmes, 30029, France
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Other studies related to the condition(s) this trial covers.
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