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Supercharged immune cells take on melanoma in new combo therapy trial

NCT ID NCT02621021

First seen Nov 20, 2025 · Last updated Jun 13, 2026 · Updated 32 times

Summary

This study tests whether adding the drug pembrolizumab to a treatment that uses a patient's own immune cells (called TIL therapy) can shrink tumors in people with advanced melanoma. About 53 adults aged 18 to 72 who have already tried at least one other treatment will take part. The approach involves removing some tumor tissue, growing immune cells from it in a lab, and returning them to the patient along with chemotherapy and other supportive drugs.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

Conditions

The condition(s) this trial relates to.

melanoma skin neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.