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Could a one-two punch of immune cells and a drug beat back melanoma?

NCT ID NCT02621021

First seen Nov 20, 2025 · Last updated Apr 29, 2026 · Updated 22 times

Summary

This study tests whether adding the drug pembrolizumab to a treatment that uses a patient's own immune cells (called TIL therapy) can shrink tumors in people with advanced melanoma that has spread. About 170 adults aged 18 to 72 with skin melanoma that hasn't responded to prior treatment will take part. Participants receive chemotherapy, then their own lab-grown immune cells plus pembrolizumab (for some), followed by recovery and follow-up visits.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

Conditions

Explore the condition pages connected to this study.