Online diet program shows promise for fatty liver
NCT ID NCT06503120
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a 12-week online Mediterranean diet program could reduce liver fat in people with a type of fatty liver disease (MASLD). 78 adults followed either the diet program or received standard advice. The goal was to see if the diet could improve liver health and related measures like blood sugar and cholesterol.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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78 people
The number who actually took part.
- Started
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Aug 2024
- Expected to finish
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Mar 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Willing to change diet for at least three months (accepting reduced sugar, less processed foods, reduced red meat, and following a Mediterranean diet with olive oil, high-fiber foods, vegetables, fruits, nuts, and legumes) * Intrahepatic triglyceride content (IHTG) of 5% * Age 18 to 70 years * Fulfill the diagnosis of Metabolic Dysfunction-Associated Steatotic Liver Disease * Baseline Mediterranean Diet Adherence Screener (T-MEDAS) score equal to or less than 5 * Participants must not have initiated any new probiotic treatment in the past three months or must have been on a stable probiotic regimen for at least three months, which they are willing to continue for the duration of the study Exclusion Criteria: * Other liver disease (viral hepatitis, autoimmune or cholestatic liver disease, Wilson's disease, hemochromatosis, or alpha-1 anti-trypsin deficiency) * Unstable body weight (variation \>5% within the preceding 3-month period) * Current use of weight loss medications (e.g., Liraglutide) * Current use of pioglitazone * Unstable diabetes (HbA1c \>8.5%) * Decompensated cirrhosis (international normalized ratio \>1.3, platelets \<100 × 109/mm, bilirubin \>20 mmol/L, albumin \<35 g/L, ascites, or hepatic encephalopathy) * A serum creatinine level ≥ 2mg/dL * Presence of active cancer or undergoing chemotherapy either at present or in the prior three years * Major illness that might require hospitalization * Pregnancy or lactation for women * Participation in another trial * Chronic treatment with warfarin (given its interaction with vitamin K) * Being implanted with a pacemaker or platinum implant (due to inability to undergo magnetic resonance imaging included in the study design) * Alcohol consumption above 30 g per day in men or 20 g per day in women
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Taichung Veterans General Hospital
Taichung, Taichung, 407219, Taiwan
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Other studies related to the condition(s) this trial covers.
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