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Doctors step into virtual exam room to test genetic dosing decisions

NCT ID NCT02108041

Knowledge-focused Sponsor: National Human Genome Research Institute (NHGRI) Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Sep 17, 2026 · Updated 11 times

Summary

This study looked at how doctors make decisions about dosing the blood thinner warfarin based on a patient's genetic background. Researchers used virtual reality to simulate patient visits with different racial and socioeconomic backgrounds. 196 internal medicine residents participated in the 60-minute session. The goal was to understand how personalized medicine is used in practice.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help train doctors to better use genetic testing for personalized drug dosing.
What could go wrong
This is a small, completed observational study with healthy doctors in a virtual setting, not a real patient trial. Results may not reflect actual clinical practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

196 people

The number who actually took part.

Finished

Oct 2020

Lead sponsor

A government research agency

The lead sponsor is the US National Institutes of Health.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Internal medicine and family medicine residents will be recruited from diverse national sites for the study, and the virtual reality environment will be brought to them through the use of a head-mounted display and laptop

Ages

21 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

* INCLUSION CRITERIA: * All physicians will be healthy adult volunteers who are medical residents in the internal medicine specialty. EXCLUSION CRITERIA: 1. persons with seizure or vestibular disorders; 2. persons who are highly prone to motion sickness; 3. those without normal or normal to corrected vision or hearing; 4. all current and past employees and contractors of NHGRI; and 5. persons who have received information about the study purpose or procedure from a past participant. NHGRI employees are excluded for this protocol because they are likely to have specialized genomic knowledge and may think differently about genomics in the clinical interaction.

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Conditions

The condition(s) this trial relates to.

thrombotic disease venous thromboembolism Venous Thrombosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Blood clots Deep vein thrombosis

Contacts and locations

Locations

  • Columbia University

    New York, New York, 10032-3784, United States

  • Harvard School of Public Health

    Boston, Massachusetts, 02115, United States

  • Johns Hopkins School of Medicine

    Baltimore, Maryland, 21205, United States

  • Michigan State University

    Flint, Michigan, United States

  • University of Oregon

    Eugene, Oregon, United States

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