New therapy helps chinese cancer patients find purpose amid pain
NCT ID NCT02112188
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study adapts a type of counseling called Meaning-Centered Psychotherapy for Chinese immigrants with advanced cancer. The goal is to help patients maintain a sense of meaning and purpose in life despite their illness. Researchers will interview and test the adapted program with 84 participants to see if it reduces emotional suffering and improves well-being.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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84 people
The number who actually took part.
- Started
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Apr 2014
- Expected to finish
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Feb 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Phase I participants will be recruited through MSKCC and referrals provided by Qcc, CCHC, ACS Asian Initiatives, CBWCHC, NYHQ and NYCAAMH and the Cheung and Kan Medical Group. Phase 3 and 4 participants will be recruited through MSKCC and referrals provided by community clinicians/collaborating partners. Flyers (Phase 3, Appendix H) in Chinese announcing the study will be distributed through MSKCC and community organizations and hospitals (e.g., QCC, WCMC, NYP LMH, CCHC, ACS Asian Initiatives, CBWCHC, NYHQ, the Cheung and Kan Medical Group and NYCAAMH).
- Ages
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21 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Phases 1 and 2: Interview Inclusion Criteria (per self-report): * Non-US born; * Of Chinese descent; * Age 21 years through 80 years; * Language spoken: Mandarin and/or English * Diagnosis of Stage IV cancer (any type). Phase 3: * Stage III or IV cancer (per self-report or on the MSKCC EMR). If traditional staging does not apply (i.e. for leukemia), we can allow patient deemed by provider to have poor prognosis/roughly equivalent to Stage III or IV to be referred. * Age 18 or older * Of Chinese descent * Mandarin-speaking * Have an estimated life expectancy of at least 6 months (per self-report or on the MSKCC EMR) * Resides in New York State or New Jersey Phase 4: * Stage III or IV cancer (per self-report or on the MSKCC EMR). If traditional staging does not apply (i.e. for leukemia), we can allow patient deemed by provider to have poor prognosis/roughly equivalent to Stage III or IV to be referred. * Age 18 or older * Of Chinese descent * Mandarin-speaking * Have an estimated life expectancy of at least 6 months (per referring physician assessment or on the MSKCC EMR) * Resides in New York State or New Jersey Exclusion Criteria: Phases 1 and 2: * Presence of cognitive impairment disorder (e.g., delirium or dementia) sufficient to preclude meaningful informed consent and/or data collection. The Chinese version of the Mini Mental State Examination (MMSE) (46) will be used as a cognitive screening tool. Patients with MMSE scores below 20 will be excluded. For English speaking patients we will use the English version of the MMSE. * Has a household member who has already participated (or agreed to participate). Phase 3: * Previous participation in Phases 1 or 2 of the study * Unable/unwilling to use or no access to a telehealth platform (i.e., telephone or videoconference) * For participants who express interest in RSMI, unable/unwilling to use Zoom videoconferencing platform * Unable or unwilling to commit to up to 16 weeks to complete 6-session intervention and follow-up assessments * Major psychiatric illness or cognitive impairment that in the judgment of study investigators or study staff would preclude study participation * Patients diagnosed with primary brain tumors (per self-report or on the MSKCC EMR), as they may have difficulty completing the intervention and answering questionnaires * Undergoing hematopoietic stem cell transplantation (HSCT) (per self-report or on the MSKCC EMR) * Currently in psychotherapeutic treatment (patients being treated with psychotropic medications will not be excluded, as long as they are not in psychotherapy; per self report) Phase 4: * Previous participation in Phases 1, 2, or 3 of the study * Unable/unwilling to use or no access to the Zoom videoconferencing platform (required for RSMI) * Unable or unwilling to commit to up to 16 weeks to complete 6-session intervention and follow-up assessments * Major psychiatric illness or cognitive impairment that in the judgment of study investigators or study staff would preclude study participation * Patients diagnosed with primary brain tumors (per self-report or on the MSKCC EMR), as they may have difficulty completing the intervention and answering questionnaires * Undergoing hematopoietic stem cell transplantation (HSCT) (per self-report or on the MSKCC EMR) * Currently in psychotherapeutic treatment (patients being treated with psychotropic medications will not be excluded, as long as they are not in psychotherapy; per self report)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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City College of New York (Data Collection AND Data Analysis)
New York, New York, 10031, United States
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MSK at Ralph Lauren (Limited Protocol Activities)
New York, New York, 10035, United States
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Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)
Basking Ridge, New Jersey, 07920, United States
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Memorial Sloan Kettering Bergen (Limited Protocol Activities)
Montvale, New Jersey, 07645, United States
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
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Memorial Sloan Kettering Cancer Center Suffolk- Commack (Limited Protocol Activities)
Commack, New York, 11725, United States
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Memorial Sloan Kettering Monmouth (Limited Protocol Activities)
Middletown, New Jersey, 07748, United States
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Memorial Sloan Kettering Nassau (Limited Protocol Activities)
Uniondale, New York, 11553, United States
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Memorial Sloan Kettering Westchester (Limited Protocol Activities)
Harrison, New York, 10604, United States
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