New endoscopy method may spot stomach cancer earlier
NCT ID NCT02738294
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether a special endoscopy technique called ME-NBI (magnifying endoscopy with narrow band imaging) can better diagnose early stomach cancer than the standard white light biopsy. Researchers looked at 211 patients with suspicious stomach lesions. They compared the accuracy of ME-NBI targeted biopsy against standard forceps biopsy, using final surgical specimens as the gold standard.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- ME-NBI (magnifying endoscopy with narrow band imaging) device
- What this could lead to
- If successful, this could show that ME-NBI targeted biopsy is more accurate than standard white light biopsy for diagnosing early gastric cancer, potentially reducing unnecessary biopsies.
- What could go wrong
- This is a completed study with 211 participants, so results are available but may not apply to all patients or settings. The technique requires specialized equipment and training.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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211 people
The number who actually took part.
- Start date
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Jun 2013
- Finished
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Dec 2015
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * consecutive patients with gastric lesions detected by white light endoscopy and suspected of EGC Exclusion Criteria: * they had advanced gastric cancer * lesions were histopathologically confirmed to be submucosal tumors * they had a history of gastrectomy * tissue biopsy wasn't obtained or more than 2 biopsies were performed on suspected gastric lesions during last white light endoscopy * they couldn't tolerate another endoscopic examination
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Departments of Gastroenterology and Clinical Laboratory, Shanghai Renji Hospital, Shanghai Jiaotong University School of Medicine
Shanghai, 200001, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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