New supplement MB-1 aims to shed pounds in overweight adults

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Males \& females aged 18-50 years, inclusive 2. BMI of 25.0 to ≤ 34.9 kg/m² 3. Females not of child-bearing potential, defined as those who have undergone a sterilization procedure (e.g. hysterectomy, bilateral oophorectomy, bilateral tubal ligation, complete endometrial ablation) or have been post-menopausal for at least 1 year prior to screening Or, Individuals of child-bearing potential must have a negative baseline urine pregnancy test and agree to use a medically-approved method of birth control for the duration of the study. All hormonal birth control must have been in use for a minimum of three months. Acceptable methods of birth control include: * Hormonal contraceptives including oral contraceptives, hormone birth control patch (Ortho Evra), vaginal contraceptive ring (NuvaRing), injectable contraceptives (Depo-Provera, Lunelle), or hormone implant (Norplant System) * Double-barrier method * Intrauterine devices * Non-heterosexual lifestyle and agrees to use contraception if planning on changing to heterosexual partner(s) * Vasectomy of partner at least 6 months prior to screening * Abstinence and agrees to use contraception if planning on becoming sexually active during the study 4. Stable body weight defined as a \<5% change in body weight in the three months prior to baseline as assessed by the QI 5. Abdominal obesity: Waist circumference of \> 94 cm (37 inches) in men and \> 80 cm (31.5 inches) in women 6. Willingness to complete questionnaires, records and diaries associated with the study and to complete all clinic visits 7. Agrees to maintain current lifestyle habits (diet, medications, supplements, and sleep) as much as possible throughout the study 8. Provided voluntary, written, informed consent to participate in the study 9. Healthy as determined by medical history as assessed by Qualified Investigator (QI) Exclusion Criteria: 1. Individuals who are pregnant, breast feeding, or planning to become pregnant during the study 2. Allergy, sensitivity, or intolerance preventing consumption of the investigational product or placebo ingredients 3. Gastric bypass surgery or other surgeries to induce weight loss 4. Metal implants or other physical characteristics/limitations that may affect DEXA scan results as assessed by the QI 5. Currently taking weight loss medications or participated in a weight loss program within the past three months as assessed by the QI 6. Current or history of eating disorders as assessed by the QI 7. Unstable metabolic disease or chronic diseases as assessed by the QI 8. Current or history of any significant diseases of the gastrointestinal tract as assessed by the QI 9. Unstable hypertension. Treatment on a stable dose of medication for at least 3 months will be considered by the QI 10. Participants residing in the same household as another study participant unless they are enrolled consecutively (e.g. not actively enrolled at the same time) 11. Type I or Type II diabetes 12. Significant cardiovascular event in the past 6 months. Participants with no significant cardiovascular event on stable medication may be included after assessment by the QI on a case-by-case basis 13. History of or current diagnosis with kidney and/or liver diseases as assessed by the QI on a case-by-case basis, with the exception of history of kidney stones in participants who are symptom free for 6 months 14. Self-reported confirmation of current or pre-existing thyroid condition. Treatment on a stable dose of medication for at least 3 months will be considered by the QI 15. Self reported confirmation of glaucoma 16. Major surgery in the past 3 months or individuals who have planned surgery during the course of the study. Participants with minor surgery will be considered on a case-by-case basis by the QI 17. Cancer, except skin basal cell carcinoma completely excised with no chemotherapy or radiation with a follow up that is negative. Volunteers with cancer in full remission for more than five years after diagnosis are acceptable 18. Individuals with an autoimmune disease or are immune compromised as assessed by the QI 19. Self-reported confirmation of a HIV-, Hepatitis B- and/or C-positive diagnosis as assessed by the QI 20. Self-reported confirmation of blood/bleeding disorders as assessed by the QI 21. Chronic use of cannabinoid products (\>2 times/week) as assessed by the QI. Occasional users will be required to washout and abstain for the duration of the study period 22. Regular use of tobacco or nicotine products in the past six months, as assessed by the QI. Occasional users will be required to washout and abstain for the duration of the study period 23. Alcohol intake average of \>2 standard drinks per day as assessed by the QI 24. Alcohol or drug abuse within the last 12 months 25. Current use of prescribed and/or over-the-counter (OTC) medications, supplements, and/or consumption of food/drinks that may impact the efficacy and/or safety of the investigational product (Section 7.3) 26. Blood donation 30 days prior to baseline, during the study, or a planned donation within 30 days of the last study visit 27. Participation in other clinical research studies 30 days prior to baseline, as assessed by the QI 28. Individuals who are unable to give informed consent 29. Any other condition or lifestyle factor, that, in the opinion of the QI, may adversely affect the participant's ability to complete the study or its measures or pose significant risk to the participant