Turkey study reveals hidden fatty liver burden in overweight adults
NCT ID NCT07548970
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at how common Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) is among 459 adults in Turkey who are at risk due to being overweight, having diabetes, or other metabolic issues. Researchers used a special ultrasound to measure liver fat and stiffness, and collected information on diet, activity, and blood markers. The goal was to find undiagnosed cases and understand what factors are linked to the disease.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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459 people
The number who actually took part.
- Started
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Jan 2023
- Finished
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Dec 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
459 male and female participants aged between 18-80, who can sign the informed consent and are eligible to participate.
- Ages
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18 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: One of the following conditions: * BMI ≥ 25 kg/m2 OR WC\> 94 cm (M) 80 cm (F) * Fasting serum glucose ≥ 100 mg/dL OR 2-hour post-load glucose levels ≥140 mg/dL OR HbA1c ≥ 5.7% OR type 2 diabetes OR treatment for type 2 diabetes * Blood pressure ≥ 130/85 mmHg OR specific antihypertensive drug treatment * Plasma triglycerides ≥ 150 mg/dL OR lipid lowering treatment * Plasma HDL-cholesterol ≤40 mg/dL (Male) and ≤ 50 mg/dL (Female) OR lipid lowering treatment Exclusion Criteria: * Excessive alcohol use (more than 20 g/day for women and 30g/day for men= \>2 glasses alcohol/day for women and \>3 glasses for men) * Hepatitis B virus, * Hepatitis C virus, * Autoimmune hepatitis, * Primary biliary cirrhosis, * Hemochromatosis, * Wilson's disease, * Alpha 1 antitrypsin deficiency * HCV Genotype 3, * Total parental nutrition, * Current use of hepatotoxic medications (amiodarone, tamoxifen, methotrexate, corticosteroids and HAART), * Celiac disease, * Pregnancy and breastfeeding * A history of bariatric surgery * Current diagnosis of liver cirrhosis and/or hepatocellular carcinoma. * Current diagnosis of extrahepatic malignancy(s) or prior diagnosis within last 5 years.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Temel Tıp Bilimleri
Istanbul, Turkey (Türkiye)
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