New drug combo aims to melt liver fat in MASH patients

NCT ID NCT07288138

Recruiting now Disease control Sponsor: Eccogene Source: ClinicalTrials.gov ↗

First seen Jan 06, 2026 · Last updated May 22, 2026 · Updated 25 times

Summary

This study tests two experimental drugs, ECC4703 and ECC0509, alone or together, to see if they can reduce fat buildup in the liver of people with MASH (a serious fatty liver disease). About 160 adults with MASH will take the drugs or a placebo for 12 weeks. The main goal is to measure changes in liver fat using a special MRI scan.

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Contacts and locations

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Study contacts

Contact

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Locations

ARK Clinical Research - Fountain Valley
RECRUITING

Fountain Valley, California, 92708, United States
ARcare Center for Clinical Research
RECRUITING

Little Rock, Arkansas, 77205, United States
Adobe Clinical Research, LLC
RECRUITING

Tucson, Arizona, 85712, United States
Akron Gastro Research
RECRUITING

Akron, Ohio, 44333, United States
Arizona Liver Health
RECRUITING

Chandler, Arizona, 85224, United States
Arizona Liver Health - Peoria
RECRUITING

Peoria, Arizona, 85381, United States
Arizona Liver Health - Tucson
RECRUITING

Tucson, Arizona, 85712, United States
Ark Clinical Research
RECRUITING

Long Beach, California, 90815, United States
Arkansas Gastroenterology, P.A
RECRUITING

Little Rock, Arkansas, 71913, United States
Bellaire Clinical Research
RECRUITING

Bellaire, Texas, 77401, United States
Care United Research
RECRUITING

Forney, Texas, 75126, United States
CenExel - iResearch
RECRUITING

Decatur, Georgia, 30030, United States
ClinCloud, LLC
RECRUITING

Viera, Florida, 32940, United States
Coastal Research Institute
RECRUITING

Fayetteville, North Carolina, 28304, United States
Columbia Gastroenterology Associates, Llc
RECRUITING

Columbia, South Carolina, 29204, United States
DSI Research
RECRUITING

Springboro, Ohio, 45066, United States
Dallas Research Institute, LLC
RECRUITING

Farmers Branch, Texas, 75234, United States
Delta Research Partners
RECRUITING

Monroe, Louisiana, 71201, United States
Delta Research Partners, LLC
RECRUITING

West Monroe, Louisiana, 71291, United States
Digestive Health Research of North Texas, LLC
RECRUITING

Wichita Falls, Texas, 76301, United States
Digestive Research Alliance of Michiana
RECRUITING

South Bend, Indiana, 46635, United States
Digestive Research of Central Texas
RECRUITING

Waco, Texas, 76712, United States
Digestive Specialists
RECRUITING

Dayton, Ohio, 45414, United States
Evolution Clinical Trials
RECRUITING

Miami, Florida, 33122, United States
Floridian Clinical Research, LLC
RECRUITING

Miami Lakes, Florida, 33016, United States
GI Select Health Research
RECRUITING

Richmond, Virginia, 23236, United States
Gastrointestinal Associates
RECRUITING

Columbia, Missouri, 65201, United States
Gastrointestinal Specialists of Georgia, PC
RECRUITING

Marietta, Georgia, 30060, United States
Gateway GI Research, LLC
RECRUITING

St Louis, Missouri, 63141, United States
Health Awareness, Inc.
RECRUITING

Jupiter, Florida, 33458, United States
Houston Research Institute
RECRUITING

Houston, Texas, 77079, United States
Houston Research Institute - Medical Center
RECRUITING

Houston, Texas, 770004, United States
Houston Research Institute - Pasadena
RECRUITING

Pasadena, Texas, 77505, United States
Knowledge Research Center
RECRUITING

Orange, California, 92868, United States
Louisiana Research Center, LLC
RECRUITING

Shreveport, Louisiana, 71105, United States
Metabolic Research Institute
RECRUITING

West Palm Beach, Florida, 33401, United States
Mid-Atlantic GI Research
RECRUITING

Greenbelt, Maryland, 20770, United States
Ocala GI Research
RECRUITING

Ocala, Florida, 34471, United States
Om Research
RECRUITING

Apple Valley, California, 92307, United States
Pinnacle Clinical Research
RECRUITING

Austin, Texas, 78757, United States
Pinnacle Clinical Research
RECRUITING

Corpus Christi, Texas, 78404, United States
Pinnacle Clinical Research
RECRUITING

San Antonio, Texas, 78229, United States
Pinnacle Clinical Research - Georgetown
RECRUITING

Georgetown, Texas, 78626, United States
Pinnacle Clinical Research - South San Antonio
RECRUITING

San Antonio, Texas, 78222, United States
Premier Health Research
RECRUITING

Sparta, New Jersey, 07871, United States
Progressive Medical Research
RECRUITING

Port Orange, Florida, 32127, United States
Quality Research, Inc.
RECRUITING

San Antonio, Texas, 78209, United States
South Texas Research Institute (STRI)
RECRUITING

Edinburg, Texas, 78539, United States
South Texas Research Institute (STRI) - Brownsville
RECRUITING

Brownsville, Texas, 78520, United States
Sugarland Medical Associates (Sma)
RECRUITING

Sugar Land, Texas, 77478, United States
Synergy Healthcare
RECRUITING

Bradenton, Florida, 33511, United States
Synergy Healthcare
RECRUITING

Bradenton, Florida, 34209, United States
Tandem Clinical Research
RECRUITING

Covington, Louisiana, 70433, United States
Tandem Clinical Research
RECRUITING

Houma, Louisiana, 70360, United States
Tandem Clinical Research
RECRUITING

Metairie, Louisiana, 70006, United States
Tandem Clinical Research GI, LLC
RECRUITING

Marrero, Louisiana, 70072, United States

Conditions

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METABOLIC DYSFUNCTION-ASSOCIATED STEATOHEPATITIS