New drug could ease sleep apnea without a mask
NCT ID NCT07226765
First seen Nov 11, 2025 · Last updated May 23, 2026 · Updated 27 times
Summary
This study tests a new drug, maridebart cafraglutide, to see if it can reduce breathing pauses during sleep in adults with obstructive sleep apnea who are overweight or obese and not using a CPAP machine. About 250 participants will receive either the drug or a placebo for 52 weeks. The main goal is to measure changes in the apnea-hypopnea index, which counts breathing interruptions per hour of sleep.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Advanced Sleep Research
RECRUITINGBerlin, 10117, Germany
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Aggarwal and Associates Ltd
RECRUITINGBrampton, Ontario, L6T 0G1, Canada
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Basil Clinical
RECRUITINGLaurelton, New York, 11413, United States
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CPQuali Pesquisa Clinica Ltda
RECRUITINGSão Paulo, São Paulo, 01228-000, Brazil
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CTI Clinical Research Center
RECRUITINGCincinnati, Ohio, 45212, United States
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CaRe Clinic
RECRUITINGCalgary, Alberta, T2N 4L7, Canada
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Centro Medico Teknon
RECRUITINGBarcelona, Catalonia, 08022, Spain
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Cerebrovaskularni poradna sro
RECRUITINGOstrava - Poruba, 708 00, Czechia
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Clinical Research Center Of Florida
RECRUITINGPompano Beach, Florida, 33060, United States
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Debreceni Egyetem Klinikai Kozpont
RECRUITINGDebrecen, 4032, Hungary
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Destiny Research Center
RECRUITINGPalmetto Bay, Florida, 33157, United States
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Diabeteszentrum Hamburg West
RECRUITINGHamburg, 22607, Germany
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Epic Medical Research - DeSoto
RECRUITINGDeSoto, Texas, 75115, United States
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Fakultni nemocnice Brno
RECRUITINGBrno, 625 00, Czechia
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Fukuoka University Hospital
RECRUITINGFukuoka, Fukuoka, 814-0180, Japan
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FutureSearch Trials of Neurology
RECRUITINGAustin, Texas, 78731, United States
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Gokeikai Osaka Kaisei Hospital
RECRUITINGOsaka, Osaka, 532-0003, Japan
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Goodsleep Clinic
RECRUITINGMinato-ku, Tokyo, 105-0012, Japan
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Hospital Medico Quirurgico San Rafael
RECRUITINGA Coruña, Galicia, 15006, Spain
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Hospital Quiron Madrid
RECRUITINGPozuelo de Alarcón, Madrid, 28223, Spain
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Hospital Universitari Vall d Hebron
RECRUITINGBarcelona, Catalonia, 08035, Spain
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Hospital Universitario 12 de Octubre
RECRUITINGMadrid, 28041, Spain
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Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo Hcfmusp
RECRUITINGSão Paulo, São Paulo, 05403-900, Brazil
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InnoDiab Forschung
RECRUITINGEssen, 45136, Germany
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Instituto de Pesquisa Clinica de Campinas - Ipecc
RECRUITINGCampinas, São Paulo, 13060-080, Brazil
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Kuwamizu Hospital
RECRUITINGKumamoto, Kumamoto, 862-0954, Japan
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Monash Medical Centre
RECRUITINGClayton, Victoria, 3168, Australia
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Monroe Biomedical Research
RECRUITINGMonroe, North Carolina, 28112, United States
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Nakamura Clinic
RECRUITINGUrasoe-shi, Okinawa, 901-2132, Japan
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Narodowy Instytut Kardiologii Stefana Kardynala Wyszynskiego Panstwowy Instytut Badawczy
RECRUITINGWarsaw, 04-635, Poland
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Nemocnice Rudolfa a Stefanie Benesov as
RECRUITINGBenesov U Prahy, 256 01, Czechia
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NeuroTrials Research
RECRUITINGAtlanta, Georgia, 30328, United States
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Northwest Clinical Research Center
RECRUITINGBellevue, Washington, 98007, United States
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Nucleo de Pesquisa do Rio Grande do Sul
RECRUITINGPorto Alegre, Rio Grande do Sul, 90430-001, Brazil
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Peninsula Research Associates
RECRUITINGRolling Hills Estates, California, 90274, United States
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RESM ShinYokohama Sleep and Respiratory Medical Care Clinic
RECRUITINGYokohama, Kanagawa, 222-0033, Japan
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Red-Institut GmbH
RECRUITINGOldenburg, 23758, Germany
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Reformatus Pulmonologiai Centrum
RECRUITINGTörökbálint, 2045, Hungary
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Royal Brisbane and Womens Hospital
RECRUITINGHerston, Queensland, 4006, Australia
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Saiseikai Futsukaichi Hospital
RECRUITINGChikushino-shi, Fukuoka, 818-8516, Japan
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Siteworks - Zentrum fuer klinische Studien Hannover
RECRUITINGHanover, 30449, Germany
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Siteworks - Zentrum fuer klinische Studien Karlsruhe
RECRUITINGKarlsruhe, 76137, Germany
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Sleep Therapy & Research Center
RECRUITINGSan Antonio, Texas, 78229, United States
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Sleep and Mental Clinic-Kitahiroshima
RECRUITINGKitahiroshima-shi, Hokkaido, 061-1121, Japan
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SomnoCenter Budapest Alvaszavar Kozpont
RECRUITINGBudapest, 1012, Hungary
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Teradan Clinical Trials
RECRUITINGBrandon, Florida, 33511, United States
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Valley Clinical Trials
RECRUITINGNorthridge, California, 91325, United States
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Wharton Medical Clinic
RECRUITINGHamilton, Ontario, L8L 5G8, Canada
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Woolcock Institute of Medical Research
RECRUITINGMacquarie Park, New South Wales, 2113, Australia
Conditions
Explore the condition pages connected to this study.