New gel scaffold aims to improve healing after skin cancer removal
NCT ID NCT06600152
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a new gel-like wound dressing called MAP Wound Matrix (TT101) in 40 adults who had skin cancer removed with Mohs surgery. The dressing was applied right after surgery to see if it was safe and helped wounds heal compared to a standard hydrocolloid bandage. The main goal was to check for serious side effects like infections or slow healing.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- MAP Wound Matrix (a gel-like scaffold applied to the wound)
- What this could lead to
- If it works, this could offer a new option to help wounds heal better after skin cancer surgery, potentially reducing complications.
- What could go wrong
- This is a small, early safety study with only 40 people. The new matrix may not heal wounds better than standard dressings, and there is a risk of infection or delayed healing.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
40 people
The number who actually took part.
- Started
-
Aug 2024
- Finished
-
Jul 2025
- Lead sponsor
-
A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
22 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Willing to undergo the written informed consent process prior to enrollment in this study. * At least 22 years of age at screening. * Has non-melanoma skin cancer and be scheduled for skin cancer surgery with Mohs micrographic surgery on a location suitable for secondary intention healing. * Resulting surgical wound after Mohs micrographic surgery must be at least 1 cm and no more than 4 cm in diameter (or surface area of at least 0.8 cm2 and no more than 12.6 cm2). * Resulting surgical wound after Mohs micrographic surgery must be full thickness. * Willing to return for all required follow-up visits. * Willing to follow the instructions of the Principal Investigator. Exclusion Criteria: \_ Has a confirmed diagnosis of clinically significant peripheral neuropathy. * Has uncontrolled Type I or Type II diabetes and HbA1c values greater than 8.0% within the last 6 months. * Has a known infection in the area of the Mohs micrographic surgery. * Has a known allergy to any of the components of the TT101 Device. * Is an active daily cigarette smoker. * Is pregnant or lactating. * Is a woman of child-bearing potential who is unwilling to avoid pregnancy or use an appropriate form of birth control (adequate birth control methods are defined as: topical, oral, implantable, or injectable contraceptives; spermicide in conjunction with a barrier such as a condom or diaphragm; IUD; or surgical sterilization of partner). * Has clinical evidence of Peripheral Vascular Disease (PVD) in the form of grade 2 pitting Edema or higher. * Has been diagnosed with a surgical or wound site infection within the last 6-months. * Has been diagnosed with chronic ulcer or wound within the last 12- months. * Has a remote active infection concurrent with having the Mohs micrographic surgery. * Per Investigator's discretion the subject is not appropriate for inclusion in the trial.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Non-melanoma skin cancer are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Cal Coast Dermatology
Encino, California, 91436, United States
-
Laser and Skin Surgery Center of Indiana
Indianapolis, Indiana, 46260, United States
-
Studies in Dermatology
Cypress, Texas, 77429, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a phone app stop sunburns before they start?
- Scientists map skin Cancer's inner workings to decode immunotherapy response
- Can a DNA vaccine teach the immune system to hunt melanoma?
- Can a workplace campaign shade outdoor workers from skin cancer?
- Can a placental patch help heal stubborn diabetic foot ulcers?
- Can your genes predict your melanoma risk?