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Hands-On therapy shows promise for jaw pain relief

NCT ID NCT07210957

Symptom relief Sponsor: Abant Izzet Baysal University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether manual therapy (hands-on techniques like massage and pressure) can help people with temporomandibular disorder (TMD) and neck pain. 48 adults received either manual therapy or therapeutic exercise. Researchers measured muscle thickness, pain sensitivity, jaw movement, and anxiety. The goal was to see if manual therapy offers better relief than standard exercises.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Manual therapy (myofascial release and trigger point therapy)
What this could lead to
If it works, this could point toward a simple, drug-free way to ease jaw pain and improve jaw function for people with TMD.
What could go wrong
This is a small, completed study with only 48 people. Results may not apply to everyone, and manual therapy may not work better than other treatments like exercise.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

48 people

The number who actually took part.

Started

Nov 2024

Finished

Jul 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 50 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Myalgia, and both myalgia and arthralgia according to Diagnostic Criteria for Temporomandibular Disorders * Completing signing the informed consent form Exclusion Criteria: * Any rheumatological or metabolic disease * Receiving any treatment for temporomandibular joint in the last 2 years (such as botulinum toxin, manual therapy, splint, orthodontics) * A history of traumatic temporomandibular joint * A history of diagnosed psychological diseases

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Conditions

The condition(s) this trial relates to.

Neck Pain temporomandibular joint disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Neck pain Temporomandibular disorder

Contacts and locations

Locations

  • Bolu Abant Izzet Baysal University Department of Physiotherapy and Rehabilitation

    Bolu, 14300, Turkey (Türkiye)

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