Sugar solution tested for safer eye surgery
NCT ID NCT07605260
First seen Jun 25, 2026 · Last updated Jul 23, 2026 · Updated 3 times
Summary
This study tested whether giving mannitol (a sugar solution) through a vein before cataract surgery improves eye pressure and the depth of the front chamber of the eye. Sixty adults aged 30-80 who were having cataract surgery took part. Half received mannitol and half received a placebo, and the researchers compared changes in eye measurements and complications.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Mannitol
- What this could lead to
- If mannitol works well, it could become a standard option to make cataract surgery safer and easier for patients.
- What could go wrong
- This is a small, completed study with only 60 participants. Results may not apply to everyone, and mannitol can have side effects like dehydration or electrolyte imbalance.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
60 people
The number who actually took part.
- Started
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Jan 2026
- Finished
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Jun 2026
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
30 to 80 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients of any gender * Aged 30-80 years * Undergoing cataract surgery Exclusion Criteria: * Patients with glaucoma, uveitis, or corneal pathology * With trauma * Previously had surgery * With exfoliation syndrome * Had iridotomies * Had use of sympathetic α1 antagonist
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Pakistan Air Force (PAF) hospital
Islamabad, Punjab Province, 44000, Pakistan
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- A lens that could let cataract patients see near and far without glasses
- One operation for cataract and glaucoma? eye surgeons test a Two-in-One approach
- Eye drops may shield the cornea after cataract surgery
- A simple blood draw might reveal hidden eye lymphoma
- Can a new lens make glasses obsolete after cataract surgery?
- Can a new lens design sharpen vision after macular surgery?