Which drug stops Post-Surgery shivers fastest? new trial aims to find out
NCT ID NCT07377903
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This trial tests three common drugs—dexmedetomidine, magnesium sulfate, and ondansetron—to see which one stops shivering fastest after spinal anesthesia. Sixty adults having lower body surgery will receive one of the drugs, and researchers will measure how quickly shivering stops and whether it returns. The goal is to find a safe, effective option to improve patient comfort after surgery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- dexmedetomidine, magnesium sulfate, ondansetron
- What this could lead to
- If successful, this could identify a fast, effective drug to stop post-anesthesia shivering, improving patient comfort and recovery.
- What could go wrong
- This is a small, early-phase trial (60 people) comparing existing drugs, so results may not apply to all patients. Side effects like low blood pressure or drowsiness are possible.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
-
Feb 2026
An estimate. Start dates often move.
- Expected to finish
-
Sep 2026
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 45 years
- Sex
-
Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age from 18 to 45 years. * Both sexes. * American Society of Anesthesiologists physical status I, II * Scheduled for elective lower abdominal or lower limb surgeries under spinal anesthesia Exclusion Criteria: * Patients with known allergy to study drugs. * Patients with baseline body temperature outside the normal range (36-37.5°C). * History of thermoregulatory disorders, thyroid dysfunction, or neurological diseases. * Patients receive sedatives, antipsychotics, or antidepressants. * Patients require intraoperative conversion to general anesthesia.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Shivering, spinal anesthesia are added.
Genom att skicka in godkänner du våra Användarvillkor
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
More trials for these conditions
Other studies related to the condition(s) this trial covers.