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Magnesium pills may improve blood sugar in type 2 diabetes

NCT ID NCT05774015

Disease control Sponsor: Sultan Qaboos University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested whether taking magnesium oxide tablets (500 mg daily) for up to 12 months could improve blood sugar control in adults with type 2 diabetes. Researchers measured changes in HbA1c and fasting blood glucose, and tracked hospital visits. The goal was to see if magnesium, guided by a specific blood test (ionized magnesium), could help manage diabetes better than a placebo.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Magnesium oxide tablets (500 mg, 302 mg elemental magnesium)
What this could lead to
If magnesium supplements prove effective, this could offer a simple, low-cost way to help manage blood sugar in type 2 diabetes.
What could go wrong
This is a completed trial, but results are not yet widely confirmed. Magnesium supplements may not work for everyone and can cause digestive side effects. Always consult a doctor before taking supplements.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

247 people

The number who actually took part.

Started

Sep 2023

Finished

Sep 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults (≥18 years old). * Treated with oral hypoglycemic agents (OHA) ± insulin regimen. * Had HbA1c ≥ 7% in the last 3 months Exclusion Criteria: * HbA1c of \< 7%. * Fully dependent patients as per clinical frailty score * End stage renal disease (creatinine clearances (CrCl) at \< 10ml/min) * With neuromuscular disease * With active solid or hematological malignancies. * With cognitive disorders. * With the following regular medications (baloxavir marboxil, calcium/sodium polystyrene sulfate, raltegravir, or unithiol) due to X category drug-drug interaction (contraindicated combinations) when given concurrently Mg oxide

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Conditions

The condition(s) this trial relates to.

type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Magnesium disorder Type 2 diabetes

Contacts and locations

Locations

  • Mohammed AlZa'abi

    Muscat, Oman

More trials for these conditions

Other studies related to the condition(s) this trial covers.