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Citizen scientists unlock secrets of the vaginal microbiome

NCT ID NCT06912126

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study aims to understand where the vaginal microbiome comes from and how it is passed between people. Researchers will recruit 500 participants in Belgium, including women and their close contacts, to provide swabs and samples over five years. The goal is to learn how these microbes are shared and how stable they are over time.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could reveal how the vaginal microbiome is established and passed between people, pointing toward ways to improve women's health.
What could go wrong
This is an observational study, not a treatment trial. It may not lead to direct medical changes, and results depend on accurate self-sampling and long-term participation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 500 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2025

Expected to finish

Jan 2032

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Central participants and their co-participants must live in Belgium.

Ages

10 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria of Central Participants: * Adults aged 18 and over at the time of enrollment; * Sex: Female; * Pre-menopausal; * Self-reported good health (including the absence of general infection) at the beginning of the study; * Living in Belgium; * Sufficient knowledge of the Dutch language; * Consent form signed; * Participating alongside her mother and at least one additional co-participant in the study. Exclusion Criteria of Central Participants: * Current pregnancy or planned pregnancy at the beginning of the study; * Current diagnosis of cancer and/or immunosuppressive therapy in the 6 months before the study; * Clinically significant abnormalities of the reproductive organs or any other medical condition at the discretion of the principal investigator; * Use of oral/vaginal antibiotics/antifungals in the 2 months before the beginning of the study; * Use of oral/vaginal pre-, pro-, post- and/or synbiotics in the 2 weeks before the beginning of the study; * Vaginal showering during the study; * Participation in an intervention study. Inclusion Criteria of Co-participants: * Closely related to or interacting with the central participant of the network at least during the last six months or more before the study, e.g. her mother, aunts, female cousins, sisters, daughters, housemates, partners or close friends; * Aged 18 or over at the time of enrollment; OR 10 or over if the co-participant's mother is also participating in the study; * Sex: Female; OR male aged 18 and over who is the partner or one of the partners (in case of polygamous relationships) of the central participant; * Self-reported good health (including the absence of general infection); * Sufficient knowledge of the Dutch language; * Consent form signed. Exclusion Criteria of Co-participants: * Use of oral/vaginal antibiotics/antifungals in the 2 months before the study; * Parallel participation in an intervention study; * Vaginal showering during the study; * Clinically significant abnormalities of the reproductive organs or any other medical condition that, in the opinion of the principal investigator, warrants exclusion from the study.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • University of Antwerp

    RECRUITING

    Antwerp, 2020, Belgium

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