Citizen scientists unlock secrets of the vaginal microbiome
NCT ID NCT06912126
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study aims to understand where the vaginal microbiome comes from and how it is passed between people. Researchers will recruit 500 participants in Belgium, including women and their close contacts, to provide swabs and samples over five years. The goal is to learn how these microbes are shared and how stable they are over time.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could reveal how the vaginal microbiome is established and passed between people, pointing toward ways to improve women's health.
- What could go wrong
- This is an observational study, not a treatment trial. It may not lead to direct medical changes, and results depend on accurate self-sampling and long-term participation.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 500 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Apr 2025
- Expected to finish
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Jan 2032
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Central participants and their co-participants must live in Belgium.
- Ages
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10 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria of Central Participants: * Adults aged 18 and over at the time of enrollment; * Sex: Female; * Pre-menopausal; * Self-reported good health (including the absence of general infection) at the beginning of the study; * Living in Belgium; * Sufficient knowledge of the Dutch language; * Consent form signed; * Participating alongside her mother and at least one additional co-participant in the study. Exclusion Criteria of Central Participants: * Current pregnancy or planned pregnancy at the beginning of the study; * Current diagnosis of cancer and/or immunosuppressive therapy in the 6 months before the study; * Clinically significant abnormalities of the reproductive organs or any other medical condition at the discretion of the principal investigator; * Use of oral/vaginal antibiotics/antifungals in the 2 months before the beginning of the study; * Use of oral/vaginal pre-, pro-, post- and/or synbiotics in the 2 weeks before the beginning of the study; * Vaginal showering during the study; * Participation in an intervention study. Inclusion Criteria of Co-participants: * Closely related to or interacting with the central participant of the network at least during the last six months or more before the study, e.g. her mother, aunts, female cousins, sisters, daughters, housemates, partners or close friends; * Aged 18 or over at the time of enrollment; OR 10 or over if the co-participant's mother is also participating in the study; * Sex: Female; OR male aged 18 and over who is the partner or one of the partners (in case of polygamous relationships) of the central participant; * Self-reported good health (including the absence of general infection); * Sufficient knowledge of the Dutch language; * Consent form signed. Exclusion Criteria of Co-participants: * Use of oral/vaginal antibiotics/antifungals in the 2 months before the study; * Parallel participation in an intervention study; * Vaginal showering during the study; * Clinically significant abnormalities of the reproductive organs or any other medical condition that, in the opinion of the principal investigator, warrants exclusion from the study.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University of Antwerp
RECRUITINGAntwerp, 2020, Belgium
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