Can smart alerts stop Post-Surgery confusion in Memory-Impaired patients?
NCT ID NCT05777187
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether computer alerts in medical records could help prevent postoperative delirium (sudden confusion after surgery) in patients with cognitive impairment. Researchers used machine learning to identify high-risk patients and prompted anesthesiologists with 12 best practices. The trial was terminated early, so it's unclear how well the alerts worked.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Clinical decision support alerts in the electronic health record
- What this could lead to
- If successful, this approach could reduce delirium rates in surgical patients with cognitive impairment by prompting doctors to follow best practices.
- What could go wrong
- The trial was terminated early, so results are limited. The intervention relies on doctors following alerts, which may not always happen.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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7,412 people
The number who actually took part.
- Started
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Jun 2023
- Finished
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Aug 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 120 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adult patients with a history of cognitive impairment (CI) undergoing surgery at the Mount Sinai Health System. * Attending physicians, resident physicians, and nurse anesthetists at the Mount Sinai Health System receiving CDS alerts during EHR system implementation. Exclusion Criteria: * Patients will be excluded if this not their first surgery since study start, if they do not have cognitive impairment based on EHR data, or if the surgery is for organ donation. * There will be no exclusion criteria for providers or historical controls.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Mount Sinai Health System
New York, New York, 10029, United States
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