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New hope for advanced colorectal cancer: targeted drug M9140 enters early trial

NCT ID NCT06806046

First seen Nov 01, 2025 · Last updated Jun 13, 2026 · Updated 39 times

Summary

This early-phase study tests an experimental drug called M9140 in 12 Chinese patients with advanced colorectal cancer that has not responded to standard treatments. The drug works like a guided missile, delivering chemotherapy directly to cancer cells that carry a specific marker (CEACAM5). The main goals are to check safety and see if the drug can shrink tumors.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Beijing Cancer Hospital

    Beijing, China

  • The Second Affiliated Hospital of Zhejiang University School of Medicine

    Hangzhou, China

  • The Sixth Affiliated Hospital of Sun Yat-sen University

    Guangzhou, China

Conditions

The condition(s) this trial relates to.

colorectal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.