New supplement shows promise for hay fever relief
NCT ID NCT06907680
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a supplement called M-Gard can help relieve symptoms of seasonal grass pollen allergies (hay fever). Twenty healthy adults with a history of grass allergies took M-Gard or a placebo in a crossover design. Researchers measured symptom severity like nasal congestion, sneezing, and itchy eyes using rating scales.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 2
Tests whether the treatment actually works, and watches for side effects, in a larger group.
- Participants
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20 people
The number who actually took part.
- Started
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Jun 2025
- Finished
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Jan 2026
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged 18-65 years. * Generally healthy * Individuals with a history of recurrent seasonal allergic rhinitis * Positive RAST test for grass allergy * BMI 18-35kg/m2 * Able to provide informed consent * Agree not to change current diet and/or exercise routine during entire enrolment period * Agree to not participate in another clinical trial during the study period Exclusion Criteria: * Serious illness e.g., liver disease, kidney disease, heart disease, mood disorders, neurological disorders such as multiple sclerosis. * Unstable illness e.g., diabetes and thyroid gland dysfunction. * Current malignancy (excluding Basal Cell Carcinoma) or chemotherapy or radiotherapy treatment for malignancy within the previous 2 years. * Individuals with symptomatic perennial allergic rhinitis, non-allergic rhinitis, chronic respiratory conditions (e.g., asthma, chronic obstructive pulmonary disease). * Participants with cognitive damage. * Acute illness experienced in the past 1 month. * Active smokers and/or nicotine or drug abuse. * Allergic to any of the ingredients in the active or placebo formula. * Chronic past and/or current alcohol use (\>21 alcoholic drinks per week) * Attempting to conceive, pregnant or lactating women * Use of medications that would affect the immune and/or the inflammatory response e.g. immunotherapy, antihistamines (daily use), corticosteroids, mast cell stabilizers, leukotriene modifiers, and decongestants. * Currently taking Coumadin (Warfarin), Heparin, Dalteparin, Enoxaparin or other anticoagulation therapy including low dose aspirin; tricyclic antidepressants; Clonidine and other central acting alpha-2-agonists. * Participants who are currently participating in any other clinical trial or who have participated in any other clinical trial during the past 1 month. * Any condition which in the opinion of the investigator makes the participant unsuitable for inclusion.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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RDC Clinical
Brisbane, Queensland, 4006, Australia