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Blood marker may reveal bone lesions in myeloma patients

NCT ID NCT02800954

First seen Nov 19, 2025 · Last updated Jun 23, 2026 · Updated 38 times

Summary

This study looked at whether a substance called M-CSF in the blood can indicate bone damage in people with multiple myeloma. Researchers compared M-CSF levels in 111 participants: those with multiple myeloma, those with a pre-cancer condition called MGUS, and healthy controls. The goal was to see if M-CSF could be a new marker for bone lesions, which are common and serious in myeloma.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • CH Beauvais

    Beauvais, 60021, France

  • CHU Amiens

    Amiens, 80054, France

  • Ch Saint Quentin

    Saint-Quentin, 02321, France

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could lead to a simple blood test to detect bone damage in multiple myeloma patients earlier.

What could go wrong

This is an observational study, not a treatment trial. It is small and may not confirm M-CSF as a reliable marker.

Conditions

The condition(s) this trial relates to.

monoclonal gammopathy of uncertain significance plasma cell myeloma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.