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Breathing technique may enhance lymphedema therapy in breast cancer survivors

NCT ID NCT07676045

Symptom relief Sponsor: University of Lahore Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time

Summary

This study investigates whether adding diaphragmatic breathing exercises to standard manual lymphatic drainage (MLD) therapy reduces arm swelling and pain better than MLD alone in women who developed lymphedema after a radical mastectomy. Participants are female breast cancer survivors aged 18 to 65 with stage I or II lymphedema. The trial measures changes in arm circumference, shoulder movement, pain levels, and daily function over four weeks of treatment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Manual lymphatic drainage and diaphragmatic breathing exercises
What this could lead to
If effective, this combination therapy could offer a simple, drug-free way to reduce lymphedema swelling and improve arm function after breast cancer surgery.
What could go wrong
This is a small, early-stage trial with 58 participants, so results may not apply to everyone. The benefits of adding breathing exercises may be modest or not clinically significant.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 58 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2026

Expected to finish

Oct 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Female patients aged 18 to 65 years. * Patients diagnosed with unilateral upper limb lymphedema secondary to radical mastectomy. * Patients with stage I or stage II lymphedema. * Patients who provide written informed consent to participate in the study Exclusion Criteria: * Patients with bilateral upper limb lymphedema. * Presence of active, recurrent, or metastatic cancer. * Acute skin infections or cellulitis in the affected upper extremity. * Severe cardiac conditions, congestive heart failure, or unstable deep vein thrombosis (DVT). * Patients who have undergone specialized physical therapy or manual lymphatic drainage for lymphedema within the past 3 months.

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Conditions

The condition(s) this trial relates to.

Breast Cancer Lymphedema lymphedema

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Breast cancer-related lymphedema

Contacts and locations

Locations

  • Femwell Physiotherapy Clinic

    Lahore, Punjab Province, Pakistan

More trials for these conditions

Other studies related to the condition(s) this trial covers.