New IV drug hopes to regrow hair in severe alopecia
NCT ID NCT07533006
First seen Apr 23, 2026 · Last updated Jun 23, 2026 · Updated 10 times
Summary
This study tests a new drug called LY4005130 for adults with severe alopecia areata, a condition causing significant hair loss. About 60 participants will receive either the drug or a placebo intravenously. The goal is to see if the drug can regrow hair and to check for side effects over about 48 weeks.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Locations
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Beijing Friendship Hospital Affiliate of Capital University
NOT_YET_RECRUITINGBeijing, 100050, China
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Brigham and Women's Hospital
NOT_YET_RECRUITINGBoston, Massachusetts, 02115, United States
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Center For Dermatology Clinical Research, Inc.
RECRUITINGFremont, California, 94538, United States
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Centrum Badan Klinicznych PI-House sp. z o.o.
NOT_YET_RECRUITINGGdansk, 80-546, Poland
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Centrum Medyczne Ginemedica
NOT_YET_RECRUITINGWroclaw, 50-414, Poland
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Chelsea and Westminster Hospital NHS Foundation Trust
NOT_YET_RECRUITINGLondon, SW10 9NH, United Kingdom
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Chung-Ang University Hospital
NOT_YET_RECRUITINGDongjak-gu, 06973, South Korea
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Cura Clinical Research - Santa Clarita - Kelly Johnson Parkway
NOT_YET_RECRUITINGSanta Clarita, California, 91355, United States
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Dar Clinical Research - Ottawa - Hunt Club Road
RECRUITINGOttawa, K1V 1C1, Canada
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Dermedic Jacek Zdybski
NOT_YET_RECRUITINGOstrowiec Świętokrzyski, 27-400, Poland
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Diamond Clinic
NOT_YET_RECRUITINGKrakow, 31-559, Poland
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Erasmus Medisch Centrum
NOT_YET_RECRUITINGRotterdam, 3015 GD, Netherlands
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Health Clinical Research, LLC
RECRUITINGCutler Bay, Florida, 33189, United States
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Huashan Hospital, Fudan University
NOT_YET_RECRUITINGShanghai, 200040, China
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Inha University Hospital
NOT_YET_RECRUITINGIncheon, 22332, South Korea
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Jeonbuk National University Hospital
NOT_YET_RECRUITINGJeonju, 54907, South Korea
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Jordan Valley Dermatology & Research Center
RECRUITINGSouth Jordan, Utah, 84095, United States
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Kelowna Health and Memory Centre
RECRUITINGKelowna, V1Y 5A8, Canada
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Kyung Hee University Hospital at Gangdong
NOT_YET_RECRUITINGSeoul, 05278, South Korea
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Northridge Clinical Trials
RECRUITINGNorthridge, California, 91325, United States
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Revival Research Institute, LLC
RECRUITINGTroy, Michigan, 48084, United States
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Royal London Hospital
NOT_YET_RECRUITINGLondon, E1 1FR, United Kingdom
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Ryan Clinical Research Inc.
NOT_YET_RECRUITINGNewmarket, L3Y 5G8, Canada
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SIMa Recherche
NOT_YET_RECRUITINGVerdun, H4G 2L8, Canada
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Salford Royal Hospital
NOT_YET_RECRUITINGSalford, M6 8HD, United Kingdom
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Seoul National University Hospital
NOT_YET_RECRUITINGSeoul, 03080, South Korea
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Shanghai Skin Disease Hospital
NOT_YET_RECRUITINGShanghai, 200071, China
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Stracskin
RECRUITINGPortsmouth, New Hampshire, 03801, United States
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Texas Dermatology and Laser Specialists - San Antonio - South New Braunfels Avenue
RECRUITINGSan Antonio, Texas, 78235, United States
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Tianjin Medical University General Hospital
NOT_YET_RECRUITINGTianjin, 300052, China
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
LY4005130 (given intravenously)
What this could lead to
If it works, this could point toward a new treatment for severe hair loss from alopecia areata.
What could go wrong
This is an early phase 2 study with only 60 people, so results may not apply to everyone. Side effects are possible, and the drug may not work better than placebo.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.