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New Alzheimer's drug injected into spine shows promise in early trial

NCT ID NCT06297590

First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 22 times

Summary

This study tests a new drug called LY3954068 in people with early Alzheimer's disease. The main goal is to see if it is safe and how it affects the body. Participants will get either the drug or a placebo injected into their spinal fluid. The study lasts up to 100 weeks and involves about 48 adults.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CenExel AMRI

    RECRUITING

    Toms River, New Jersey, 08755, United States

    Contact Phone: •••-•••-••••

    Contact

  • CenExel iResearch, LLC (CenExel iRA)

    RECRUITING

    Decatur, Georgia, 30030, United States

    Contact Phone: •••-•••-••••

    Contact

  • Charter Research, LLC

    RECRUITING

    The Villages, Florida, 32162, United States

    Contact Phone: •••-•••-••••

    Contact

  • Duke University

    RECRUITING

    Durham, North Carolina, 27710, United States

    Contact Phone: •••-•••-••••

    Contact

  • K2 Medical Research, LLC

    RECRUITING

    Maitland, Florida, 32751, United States

    Contact Phone: •••-•••-••••

    Contact

  • Massachusetts General Hospital (MGH)

    NOT_YET_RECRUITING

    Charlestown, Massachusetts, 02129, United States

    Contact Phone: •••-•••-••••

    Contact

  • National Hospital for Neurology and Neurosurgery (UCLH)

    RECRUITING

    London, WC1N 3BG, United Kingdom

    Contact Phone: •••-•••-••••

    Contact

  • Royal Hallamshire Hospital

    NOT_YET_RECRUITING

    Sheffield, S10 2JF, United Kingdom

    Contact Phone: •••-•••-••••

    Contact

  • The University of Tokyo Hospital

    RECRUITING

    Bunkyō City, 113-8655, Japan

    Contact Phone: •••-•••-••••

    Contact

  • University Hospital Southampton

    NOT_YET_RECRUITING

    Southampton, SO16 6YD, United Kingdom

    Contact Phone: •••-•••-••••

    Contact

Conditions

Explore the condition pages connected to this study.