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Gene therapy injection aims to tame rare enzyme disorder in kids

NCT ID NCT06528080

First seen Feb 04, 2026 · Last updated May 22, 2026 · Updated 16 times

Summary

This early-stage study tests a single intravenous dose of LY-M001 in 9 children (ages 6 to 17) with type 1 Gaucher disease. The goal is to see if the treatment is safe and can restore the missing enzyme, potentially reducing the need for lifelong enzyme replacement therapy. Researchers will monitor side effects and measure enzyme activity in the blood for up to a year.

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Contacts and locations

Locations

  • Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University

    Shanghai, Shanghai Municipality, China

Conditions

Explore the condition pages connected to this study.