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New combo therapy aims to fight hard-to-treat blood cancers

NCT ID NCT05990465

First seen Mar 06, 2026 · Last updated Apr 30, 2026 · Updated 4 times

Summary

This early-phase study tests a new treatment for adults with B-cell lymphomas (like certain types of non-Hodgkin lymphoma) that have come back or not responded to prior therapies. The treatment combines a targeted drug called pirtobrutinib with specially engineered immune cells (LV20.19 CAR T-cells). The goal is to see if this combination is safe and can help control the cancer. About 12 participants will receive the therapy and be monitored for side effects and response.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Froedtert & the Medical College of Wisconsin

    RECRUITING

    Milwaukee, Wisconsin, 53226, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.