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Can an ancient pill tame menopause?

NCT ID NCT05846698

Symptom relief Sponsor: Guoqing Zhou Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 09, 2026 · Last updated Sep 10, 2026 · Updated 1 time

Summary

Researchers are studying whether a traditional Chinese medicine called Luo-Bu-Fu-Ke-Bi-RI Pill can ease symptoms of climacteric syndrome, the transitional phase that includes hot flashes and mood changes. The trial enrolls 300 women diagnosed with the condition and compares the pill with tibolone, a standard hormone treatment. By measuring sex hormone levels, the team aims to understand how the pill might work and whether it offers a viable alternative.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Luo-Bu-Fu-Ke-Bi-RI Pill, a traditional Chinese medicine, compared with tibolone
What this could lead to
If it works, this could offer women a plant-based option for easing menopausal symptoms, possibly with fewer side effects than standard hormone therapy.
What could go wrong
The trial is early, and many traditional remedies fail to show clear benefits in rigorous testing. Tibolone is an established treatment, so the pill may not match its effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

300 people

The number who actually took part.

Started

Sep 2021

Finished

Jun 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

female

Ages

41 to 60 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Clinical diagnosis of climacteric syndrome

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Climacteric syndrome

Contacts and locations

Locations

  • The First Affiliated Hospital of Chongqing Medical University

    Chongqing, Chongqing Municipality, 400016, China

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