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New study tests best way to keep lungs open during surgery

NCT ID NCT07186920

Knowledge-focused Sponsor: University General Hospital of Patras Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 70 adults having surgery to see if a special breathing machine setting (lowest driving pressure) prevents lung collapse better than standard protective settings. Researchers used lung ultrasound to check for collapse right after surgery. The goal was to find which method keeps lungs healthier and may reduce hospital stays or complications.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

70 people

The number who actually took part.

Started

Oct 2025

Finished

Jan 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * \>17 years old * Surgery with general anesthesia \& invasive mechanical ventilation * ASA score I-III Exclusion Criteria: * \<18 years old * Preoperative ARISCAT score estimation \<26 * Women during pregnancy or just given birth * Other type of anesthesia (Not general) * Contraindication of administration of neuromuscular blockade agents. * Contraindication of cease of spontaneous ventilation. * Mechanical ventilation without endotracheal intubation. * Severe heart failure / History of ischemic heart disease. * Moderate or severe chronic obstructive lung disease or interstitial lung disease. * History of operation in heart, lung or diaphragm. * Presence of new active pathology in respiratory system at the beginning of surgery (infection / trauma / anatomic disorder). * Severe intraoperative respiratory complication (laryngospasm / bronchospasm / anaphylaxis). * Immediate postoperative need for continuation of IMV. * Patient denial of participation in the trial.

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Conditions

The condition(s) this trial relates to.

Pulmonary Atelectasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Lung ultrasonography score Lung ultrasound Postoperative atelectasis Postoperative pulmonary atelectasis Postoperative pulmonary complications (PPCS)

Contacts and locations

Locations

  • University Hospital of Patras

    Pátrai, 26504, Greece

More trials for these conditions

Other studies related to the condition(s) this trial covers.