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Surgery ventilation study aims to find the sweet spot for lung health

NCT ID NCT07161466

Knowledge-focused Sponsor: Northern Jiangsu People's Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study looked at 101 adults having laparoscopic colorectal surgery under general anesthesia. Researchers tested different levels of positive end-expiratory pressure (PEEP) after a lung recruitment maneuver to see how long the benefits lasted and how it affected heart function. The goal is to help doctors choose the best ventilator settings to protect the lungs during surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help doctors choose the best ventilator settings during surgery to improve lung function and reduce complications.
What could go wrong
This is a small, completed study focused on short-term breathing mechanics, not long-term outcomes. Results may not apply to all surgery types or patient groups.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

101 people

The number who actually took part.

Started

Aug 2025

Finished

Nov 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * ASA physical status classification: Ⅰ or Ⅱ or Ⅲ * Adults aged 18 to 80 years, regardless of gender. * Patients undergoing elective laparoscopic colorectal cancer surgery under general anesthesia. * Patients who have provided written informed consent after understanding the study purpose, procedures, and potential risks. Exclusion Criteria: * Recent thoracic surgery; radiographic evidence of pneumothorax, emphysema, or pulmonary bullae; * Pulmonary diseases: asthma or severe obstructive ventilatory dysfunction; preoperative pulse oxygen saturation (SpO2) \< 90% on room air or \< 95% with supplemental oxygen; contraindications to ARMs (e.g., intracranial hypertension, hypovolemic shock, or right heart failure); * severe cardiac disease (NYHA class III/IV, acute coronary syndrome, sustained ventricular tachycardia); concurrent participation in another trial; or refusal to provide informed consent

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Conditions

The condition(s) this trial relates to.

colorectal cancer middle lobe syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Alveolar recruitment maneuver Dynamic lung compliance Pulmonary atelectasis

Contacts and locations

Locations

  • Northern Jiangsu People's Hospital

    Yangzhou, Jiangsu, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.