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Massive canadian study reveals gaps in lung protection during surgery

NCT ID NCT06821139

Knowledge-focused Sponsor: Perseus Missirlis Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study looked at nearly 29,000 adults who had non-cardiac surgery under general anesthesia in a large Canadian health region. Researchers wanted to see how often doctors used lung protective ventilation, a technique that uses smaller breaths and gentle pressure to reduce breathing problems after surgery. They also examined whether the COVID-19 pandemic changed how often this technique was used. The study used existing medical records to find patterns and factors that influence whether this protective approach is followed.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help hospitals improve how they use lung protective ventilation during surgery, potentially reducing breathing complications after operations.
What could go wrong
This is an observational study that looks back at past data, so it cannot prove cause and effect. Results may not apply to other hospitals or countries.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

28,700 people

The number who actually took part.

Started

Jan 2014

Finished

Dec 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients from January 2014 to December 2023, age above 18, undergoing non-cardiac and non-thoracic surgery for greater than 30 minutes with an endotracheal tube placed. Both inpatients and outpatients are eligible.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * over the age of 18 * underwent general anesthesia with endotracheal tube placement for a procedure lasting ≥30 minutes. * included in both our clinical anesthesia record database and the National Surgical Quality Improvement Program (NSQIP) database, and linkable by usual identifiers (name, date of birth, medical record number, personal health number, date of surgery) Exclusion Criteria: * no endotracheal tube utilized * cardiothoracic surgery * organ donation surgery * organ transplant recipient * Hyperthermic intraperitoneal chemotherapy * surgical procedure related to an occurrence or complication of prior procedure during the same admission/within 30 days, * multiple NSQIP assessed cases within 30 days only for same patient * cases in clinical anesthesia record database that are unable to be linked to NSQIP data or vice versa.

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Conditions

The condition(s) this trial relates to.

COVID-19

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COVID COVID -19 Intraoperative ventilation Lung-protective ventilation Non-cardiac surgery

Contacts and locations

Locations

  • Fraser Health Authority

    Surrey, British Columbia, V3T 0H1, Canada

More trials for these conditions

Other studies related to the condition(s) this trial covers.